Amino acid ferrocene conjugates using sulfonamide linkages
نویسندگان
چکیده
منابع مشابه
Quinone-Amino Acid Conjugates Targeting Leishmania Amino Acid Transporters
The aim of the present study was to investigate the feasibility of targeting Leishmania transporters via appropriately designed chemical probes. Leishmania donovani, the parasite that causes visceral leishmaniasis, is auxotrophic for arginine and lysine and has specific transporters (LdAAP3 and LdAAP7) to import these nutrients. Probes 1-15 were originated by conjugating cytotoxic quinone fragm...
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A novel synthetic approach toward a poorly explored bioorganometallic consisting of ferrocene-1,1'-diamine bearing structurally and chirally diverse amino acid sequences is reported. Until now, ferrocene-1,1'-diamine was suitable for accommodating only identical amino acid sequences at its N-termini, leading to the symmetrically disubstituted homochiral products stabilized through a 14-membered...
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Ready protease-catalyzed synthesis of carbohydrate-amino acid conjugates.
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متن کاملFerrocene conjugates of dUTP for enzymatic redox labelling of DNA.
Two ferrocene-labelled analogues of dTTP, 5-(3-ferrocenecarboxamidopropenyl-1) 2'-deoxyuridine 5'-triphosphate (Fc1-dUTP) and 5-(3-ferroceneacet-amidopropenyl-1) 2'-deoxyuridine 5'-triphosphate (Fc2-dUTP) have been produced to demonstrate the incorporation of redox labels into DNA by polymerases. Cyclic voltammetry indicates that the ferrocenyl moieties display reversible redox behaviour in aqu...
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ژورنال
عنوان ژورنال: Journal of Organometallic Chemistry
سال: 2018
ISSN: 0022-328X
DOI: 10.1016/j.jorganchem.2018.06.018